Does Covishield has any kind of side effects?

Both COVISHIELD™ (manufactured by Serum Institute of India Pvt Ltd) and COVID-19 Vaccine AstraZeneca (manufactured by AstraZeneca) are ChAdOx1 nCoV- 19 Corona Virus Vaccines.

Covishield vaccine from which country?

In countries like India and others with lower to middle incomes, a vaccine called “Covishield” was made and distributed. This vaccine was produced by the Serum Institute of India (SII) under a license from a university and a Swedish-British drugmaker. In January 2021, the Serum Institute of India (SII), a pharmaceutical company based in Pune, established a significant collaboration with AstraZeneca and the University of Oxford. This partnership aimed to manufacture the Covishield vaccine specifically for India and other nations categorized as low- and middle-income countries.

Which virus is the Covishield vaccine made of?

COVISHIELDTM is a vaccine developed as a result of a collaboration between the Serum Institute of India (SII), AstraZeneca, and the University of Oxford. It utilizes a recombinant, replication-deficient chimpanzee adenovirus vector encoding the SARS-CoV-2 Spike (S) glycoprotein.

Now, let’s delve into what the coronavirus is and how it spread globally. The coronavirus, specifically referring to SARS-CoV-2, is a novel strain that emerged in late 2019 in Wuhan, China. It belongs to a family of viruses known for causing respiratory illnesses, ranging from the common cold to more severe diseases like Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS). The spread of COVID-19, the disease caused by the coronavirus, was facilitated by human-to-human transmission through respiratory droplets when an infected person coughs, sneezes, or talks. This mode of transmission enabled the virus to rapidly spread across the globe, leading to a pandemic declared by the World Health Organization (WHO) in March 2020.

The pandemic brought about unprecedented challenges as countries implemented various measures such as lockdowns, social distancing, mask mandates, and travel restrictions to contain the spread of the virus. Amidst this crisis, scientists and pharmaceutical companies raced to develop vaccines to combat the virus. COVISHIELDTM emerged as one such vaccine, offering hope in the fight against COVID-19 by stimulating an immune response upon administration of its genetic material, thereby aiding in the prevention of severe illness and reducing transmission rates.

What are the concerns associated with the Covishield vaccine?

Previously, there have been raised concerns surrounding AstraZeneca’s COVID-19 vaccines and the occurrence of thrombosis with thrombocytopenia syndrome (TTS). AstraZeneca, a multinational pharmaceutical company, has developed the AZD1222 vaccine to combat the COVID-19 virus. This vaccine, known as Covishield when produced under license in India, has been reported to have rare adverse effects related to blood clotting and low platelet counts.

The AZD1222 vaccine, including its Indian-manufactured version Covishield, employs a chimpanzee adenovirus vector encoding the SARS-CoV-2 Spike (S) glycoprotein. After administration, this vaccine prompts the body to produce an immune response by expressing genetic material from part of the coronavirus.

However, concerns have emerged regarding its potential side effects. AstraZeneca has acknowledged the occurrence of rare cases where individuals administered with the AZD1222 vaccine developed low platelet counts and experienced blood clot formation. These adverse effects have been characterized as thrombosis with thrombocytopenia syndrome (TTS).

While the incidence of these adverse events is extremely rare, their identification has prompted further investigation and monitoring by health authorities worldwide. Regulatory bodies and healthcare professionals continue to assess the risk-benefit profile of the AstraZeneca COVID-19 vaccine, emphasizing the importance of monitoring and reporting any adverse reactions to ensure the safety and efficacy of vaccination programs.

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